![]() ![]() ![]() ![]() Such epialleles could, therefore, be subject to natural selection in the same way as conventional DNA sequence-based alleles. Moreover, bona fide heritable ‘epialleles' exist and are quite common in plants. First, some epigenetic states are transmitted intergenerationally and affect the phenotype of offspring. Nonetheless, there is growing appreciation that epigenetic variation makes direct and indirect contributions to evolutionary processes. Epigenetic mechanisms are often held to make a minor contribution to evolutionary change because epigenetic states are typically erased and reset at every generation, and are therefore, not heritable. Epigenetic mechanisms are central to gene regulation, phenotypic plasticity, development and the preservation of genome integrity. Epigenetics is the study of changes in gene activity that can be transmitted through cell divisions but cannot be explained by changes in the DNA sequence. ![]()
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